TGN46 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91340-50, BS91340-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43493(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IP,

All Applications: WB:1:1,000-1:2,000
IP:1:50-1:100
IHC:1:50-1:200

Background: TGN38 (trans-Golgi network protein 2) is a type I integral membrane protein that constitutively cycles between the TGN and plasma membrane where it partitions nascent proteins into carrier vesicles for transport to appropriate destinations in the cell. The cytosolic domain of TGN38 interacts with AP2 Clathrin adaptor complexes via the tyrosine-containing motif (SDYQRL) to direct internalization from the plasma membrane. N- and O-linked oligosaccharide chains attach to the core TGN38 protein to produce a protein present in brain, lung and kidney.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: TGN46 polyclonal antibody detects endogenous levels of TGN46 protein.

Bioworld Molecular Weight: 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TGN46 on NIH/3T3 cells lysates using anti-TGN46 antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TGN46 antibody. Counter stained with hematoxylin.

Alternative Name: TGOLN2, TGN 46, TGN 51, TGN38, TGN38 homolog, TGN46, TGN48, TGN51, TGOLN2, TGON2, Trans Golgi network integral membrane protein 2, Trans golgi network protein 2, Trans Golgi network protein TGN51, Trans-Golgi network integral membrane protein 2, Trans-Golgi network protein TGN51, TTGN2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified