BRD2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90147-50, BS90147-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P25440(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, ICC IHC FC

All Applications: WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Background: The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: BRD2 polyclonal antibody detects endogenous levels of BRD2 protein.

Bioworld Molecular Weight: Predicted band size 88 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of BRD2 on SiHa cell lysate using anti-BRD2 antibody at 1/2,000 dilution., ICC staining BRD2 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: BRD2, KIAA9001, RING3, BRD 2, Brd2, BRD2, Bromodomain containing 2, Bromodomain-containing protein 2, D6S113E, DKFZp686N0336, Female sterile homeotic related gene 1, Female sterile homeotic related gene 1, mouse, homolog of, FLJ31942, FSH, FSRG1, KIAA9001, NAT, O27.1.1, Really interesting new gene 3 protein, RING3, RING3 PROTEIN, RNF3,

Immunogen: Recombinant protein within human BRD2 aa 1-200.

Conjugate: Unconjugated

Modification: Unmodified