STIP1/HOP Rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20870-50, ES20870-100

Citations, Manuals and MSDS Available upon request.

Background: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],

Alternate Name: Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)

Source: Rabbit

Applications: IHC; WB

Dilution: IHC-p 1:50-200, WB 1:1000-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human STIP1/HOP AA range: 250-300

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 64kD

Human Gene ID: 10963

Human SWISS Prot NO: P31948

Subcellular Location: Cytoplasm. Nucleus. Dynein axonemal particle.

Research Use Only