Fas Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10909-50, MB10909-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P25445

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 38 kDa; Observed MW: 40-50 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Fas in HL-60 using Fas antibody, and DAPI., Western blot analysis of Fas in Hela, Jurkat lysates using Fas antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using Fas antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6

Immunogen: A synthetic peptide of human Fas

Conjugate: Unconjugated

Modification: Unmodified