Syntaxin 3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91309-50, BS91309-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q13277(Human) Q64704(Mouse) Q08849(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC FC

All Applications: WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100

Background: Correct vesicular transport is essential to the survival of eukaryotic cells. This process is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). This complex then recruits soluble NSF attachment proteins (SNAPs) and N-ethylmaleimide-sensitive factor (NSF) to form the highly stable SNAP receptor (SNARE) complex. The formation of a SNARE complex pulls the vesicle and target membrane together and may provide the energy to drive fusion of the lipid bilayers. Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Syntaxin 3 localizes to the apical plasma membrane and is involved in membrane fusion of apical trafficking pathways. Syntaxin 3 is a key factor in the growth of neurites, and it also functions as a direct target for arachidonic acid. Human Syntaxin 3 has two forms: Syntaxin 3A and 3B, while the mouse version has four forms: 3A, 3B, 3C, and 3D.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: Syntaxin 3 polyclonal antibody detects endogenous levels of Syntaxin 3 protein.

Bioworld Molecular Weight: 33 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Syntaxin 3 on SH-SY-5Y cell (1) and human kidney tissue (2) lysate using anti-Syntaxin 3 antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-Syntaxin 3 antibody. Counter stained with hematoxylin.

Alternative Name: STX3, STX3A, FLJ30906, Stx3, STX3, STX3A, Syntaxin 3A, Syntaxin-3,

Immunogen: Recombinant protein corresponding to cytoplasmic region of human Syntaxin 3.

Conjugate: Unconjugated

Modification: Unmodified