TNNT2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB9114-50, MB9114-100

Product: Mouse IgG2b, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P45379(Human) P50752(Mouse)

Host: Mouse

Reactivity: Human, Mouse

Applications: WB, IHC ICC

All Applications: WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200

Background: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Defects in TNNT2 are the cause of cardiomyopathy familial hypertrophic type 2 (CMH2), cardiomyopathy dilated type 1D (CMD1D) and cardiomyopathy familial restrictive type 3 (RCM3).

Purification and Purity: ProG affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: TNNT2 monoclonal antibody detects endogenous levels of TNNT2 protein.

Bioworld Molecular Weight: 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cardiac Troponin T on human heart tissue lysate using anti- Cardiac Troponin T antibody at 1/1,000 dilution., ICC staining Cardiac Troponin T (green) in A431 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: TnTc, cTnT, TNNT2, Cardiac muscle troponin T, Cardiomyopathy dilated 1D (autosomal dominant), Cardiomyopathy hypertrophic 2, CMD1D, CMH2, CMPD2, cTnT, LVNC6, MGC3889, OTTHUMP00000033864, OTTHUMP00000033865, OTTHUMP00000033866, OTTHUMP00000033867, OTTHUMP00000033870, OTTHUMP00000218095, RCM3, TNNT 2, TNNT2, TNNT2, TnTc, Troponin T cardiac muscle, Troponin T type 2 (cardiac), Troponin T type 2 cardiac, Troponin T, cardiac muscle, Troponin T2 cardiac,

Immunogen: Peptide.

Conjugate: Unconjugated

Modification: Unmodified